Brain. Health. Everyday.

At Niji Neuroscience we aim to translate cutting-edge science to practical and actionable technologies in support of clinical research and therapeutic clinical trials, as well as in the promotion of brain health.

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about us

Motivated by amazing advances in neuroscience

Every day, scientists worldwide are making significant discoveries about the brain and the positive and negative factors that impact brain health. Niji emerged from a desire to translate cutting-edge brain research into accessible technologies to support rapid discovery of novel therapeutics for neurological conditions with a focus on Alzheimer’s disease and Cerebrovascular disease.

SOLUTIONS

Neuroimaging

Consultation and support for imaging studies, including clinical trials, on image acquisition, harmonization across scanner platforms, data quality assessment, and data processing.

graphic illustration of people working in a lab

graphic illustration of people working on computers

Neuropsychological Assessment

Consultation and support including selection of appropriate tests, digital neuropsychology, scoring, data analysis, use of scores as trial outcome measures, and interpretation of results.

Digital Health

Consultation and support including remote tracking of participant cognition and health.

graphic illustration of people working with computers in a lab

graphic illustration of people working on computers in a lab

Clinical Trials

Consultation and support including study design, participant inclusion, exclusion, and enrollment, group matching and randomization, and selection of outcome measures.

Insights

What is Alzheimer’s disease?

Alzheimer’s disease is a condition that causes the cells in the brain die (referred to as ‘neurodegeneration’) ...

What is cerebrovascular disease?

Cerebrovascular disease refers to several conditions that result in a disruption of the blood supply...

What is digital health?

Digital health refers to a range of technologies that employ computer assisted procedures to facilitate...

What is brain imaging?

Brain imaging (also known as ‘neuroimaging’) refers to a range of technologies that allow clinicians and scientists to see ‘pictures’ of the living brain.

How does new technology help us find a cure?

A goal of current clinical trial research testing new therapies for Alzheimer’s disease and cerebrovascular disease is to prevent the development ...

What is digital health?

Digital health refers to a range of technologies that employ computer assisted procedures to facilitate...

What is Alzheimer’s disease?

Alzheimer’s disease is a condition that causes the cells in the brain to die (referred to as ‘neurodegeneration’) resulting in problems with memory and other forms of thinking and behaviors. In the later stages of disease, the patient loses their ability to function independently, resulting in significant challenges for the patient and their family (a condition referred to as ‘dementia’). Dementia is not the simple result of ‘getting old’; it is a disorder that most commonly occurs in individuals that have certain ‘risk factors’, such as specific risk genes. Although the memory problems due to Alzheimer’s disease typically begin in adults 60 years and older, brain changes begin anywhere from 10 to over 30 years before a diagnosis of Alzheimer’s disease is made! There is currently no cure for Alzheimer’s disease. However, early detection of neurodegeneration will be key for any future successful therapy.

What is cerebrovascular disease?

Cerebrovascular disease refers to several conditions that result in disruption of the blood supply to the brain. The brain requires more energy than any other organ in the body, and this energy comes in the form of chemicals in blood. When the blood supply is disrupted, brain tissue is vulnerable to damage due to lack of oxygen and other nutrients. When the blood supply to the brain is significantly disrupted, for example, due to blockage of the blood vessels that penetrate the brain, a major event such as a stroke can occur. ‘Stroke’ refers to disruption or damage to brain tissue due to lack of blood supply. There are often no obvious ‘warning signs’ prior to a cerebrovascular event. However, even prior to an overt stroke, there is cumulative damage to the smallest blood vessels in the brain. This damage promotes more subtle disruptions in brain function that negatively impact daily thinking and detection of such changes can be important in preventing a future stroke.

What is digital health?

Digital health refers to a range of technologies that employ computer assisted procedures to facilitate healthcare and other medically related operations. Digital health technologies can range from online testing of thinking to health monitors (for example, pulse sensors), to medical imaging software. The use of powerful computer processing and artificial intelligence allows the detailed analysis of these different health measures to help in making a medical diagnosis, or to determine if an individual is at risk for a future event, such as dementia or stroke, so that medical intervention can be performed before the negative event occurs.

How does new technology help us find a cure?

A goal of current clinical trial research testing new therapies for Alzheimer’s disease and cerebrovascular disease is to prevent the development of symptoms in individuals with very early signs of disease. Neuroscience technology can help to detect individuals exhibiting the earliest disease-related changes in the brain and/or changes in behavior. These individuals, considered to be ‘at risk’, can then be selected to participate in research to test new pharmaceuticals, devices, lifestyle changes, and other interventions that will one day lead to the prevention of these major life altering conditions.

PARTNER WITH US

Niji is seeking partners motivated to pursue outside-the-box approaches for the prevention and treatment of Alzheimer's and Cerebrovascular disease. Reach out to us!

Niji Corp.

45 Prospect St., Cambridge, MA 02139

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We are reachable by phone:

+1 508 263 0267